Research Groups


At the Institute of Molecular Biology, we are engaged in active research at the molecular and cellular level in diverse fields of developmental biology and structural biology. Main themes of research interest at the Institute have gradually taken shape through vigorous discussions and close interactions with local and overseas scientists. Affinity groups have also been established to encourage and facilitate the initiation of collaborative projects. Current research topics include:

  1. Cellular Communication and Signal Transduction ¡G Research concentrates on cell-differentiation, signal-transduction, cell-cycle, apoptosis, virus-host interactions, and protein transport in plants and animal cells.

    2. Dr. Yu-Chan Chao Dr. Ming-Zong Lai Dr. Nan-Shih Liao
    Dr. John Kung Dr. Wen Chang Dr. Hsin-Fang Yang-Yen
    Dr. Yi-Fang Tsay Dr. Chung Wang Dr. Hsou-Min Li
    Dr. Yi-Ping Hsueh
    		 Dr. Rey-Huei Chen
    		 Dr. Jun-Yi Leu

  2. Nuclear Structure and Function ¡G Projects cover mechanisms of gene regulation, RNA splicing, RNA structure-function, and cell growth control, and chromosome structure.

    3. Dr. Jaulang Hwang Dr. Sue Lin-Chao Dr. Soo-Chen Cheng
    Dr. Su-May Yu Dr. Bon-Chu Chung Dr. C.-K. J. Shen
    Dr. Meng-Chao Yao Dr. Ting-Fang Wang  

  3. Genetics and Development ¡G Focuses include the role of homeobox genes, regulation of homeotic genes, genes involved in Drosophila eye and sensory organ development, regulation and function of steroid hormone in vertebrates, neural development, and carbohydrate metabolism in plants.

    4. Dr. Henry Sun Dr. Der-Hwa Huang Dr. Jychian Chen
    Dr. Cheng-Ting Chien Dr. Hung Li Dr. Ying-Hue Lee
    Dr. Bon-Chu Chung Dr. C.-K. J. Shen Dr. Yi-Ping Hsueh

  4. Structure-Function Relationship in Biological Systems ¡G The approaches used are mainly x-ray crystallography and mass spectrometry, with the aid of computer model-building.

    5. Dr. Yen-Chywan Liaw Dr. Huey-Nan Wu Dr. Hanna S. Yuan
    Dr. Ming F. Tam Dr. Chwan-Deng (David) Hsiao Dr. Chih-Yen King
    Dr. Hung-Ta Chen    

  5. Molecular Virology¡G The study of the molecular biology and pathogenesis of various animal viruses, particularly focusing on the structure, entry process and replication of viruses and virus-host interactions with relevance to the mechanism of virus-induced signaling and diseases.

    6. Dr. Michael M. C. Lai Dr. Wen Chang

  6. Biotechnology Development¡G Research include mouse model of spinal muscular atrophy, strategy of anti-obesity, vaccine development, promoter improvement for protein expression in baculovirus and sugar regulated gene expression in rice.

    7. Dr. Hung Li Dr. Ying-Hue Lee Dr. Jaulang Hwang
    Dr. Yu-Chan Chao Dr. Su-May Yu  

 

Research Research