Our research interests are to study mammalian cell growth and metabolic controls with emphasis on studying gene functions and signaling closely linked to human diseases such as tumors and metabolic disorders. Experimental systems include using gene disruption/mutation mouse models, mammalian primary and/or established cell line models, as well as using cell-free biochemical analyses. Below are our current research directions:
1. To study the function network of genes involved in the liver cancer development by global gene expression analysis of tumor-prone mouse models.
2. To study the functional cross-talks between lipid metabolism and cell growth controls
3. To study the protein synthesis control in immune cells during activation process.