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Structural Biology

Structural Biology for Spring 2009
Course code 3024160
Credits 3 credits
Organizers Dr. David Hsiao
Purpose The purpose of this course is to bring out the structural and functional logic that has emerged from the accumulated data on protein structures.
Time Thursday, 2:00 - 4:50 pm
Place Rm. 114, Institute of Biological Chemistry, Academia Sinica

 

  Date Topic Lecturer
    Protein Crystallography
1. 2/19 (I) Crystallization, X-ray sources and detectors Chwan-Deng Hsiao (蕭傳鐙)
2. 2/26 (II) Symmetry, space group and diffraction basics Chwan-Deng Hsiao (蕭傳鐙)
3. 3/5 (III) Phase determination Chwan-Deng Hsiao (蕭傳鐙)
4. 3/12 (IV) Structural refinement and validation Chwan-Deng Hsiao (蕭傳鐙)
    Mass Spectrometry
5. 3/19 (I) Principles Kay-Hooi Khoo (邱繼輝)
6. 3/26 (II) Applications Kay-Hooi Khoo (邱繼輝)
    Cryo-Electron Microscopy  
7. 4/2 (I) Principle and application Wen-Hou Chang (章為皓)
8. 4/9 Mid-term Exam  
    NMR
9. 4/16 (I) NMR theory and experiments Der-Lii M. Tzou (鄒德里)
10. 4/23 (II) Structure determination: Protein Der-Lii M. Tzou (鄒德里)
11. 4/30 (III) Structure determination: Nucleic acid Lou-Sing Kan  (甘魯生)
    Spectroscopy
12. 5/7 (I) Principles of optical spectroscopies Chen-Yuan Dong (董成淵)
13. 5/14 (II) Principles of scanning probe microscopy Chen-Yuan Dong (董成淵)
14. 5/21 Fluorescence and bio-spectroscopic characterization of biomolecular structure and interactions Ding-KwoChang(張定國)
  5/28 Holiday, no class
    Computational Biophysics
15. 6/6 (I) Forces and structure prediction Ming-Jing Hwang (黃明經)
16. 6/11 (II) Structure comparison and classification Ming-Jing Hwang (黃明經)
17. 6/18 Final Exam