Dr. Cheng-Ting Chien 簡正鼎博士

研究著作

1. Tien, A.-C., Hsei, H.-Y., and Chien, C.-T., (1999) Dynamic expression and cellular localization of the Drosophila 14-3-3ε during embryonic development. Mech. Dev. 81, 209-212.
2. Chen, C.-K. and Chien, C.-T., (1999) Negative regulation of atonal in proneural cluster formation of Drosophila R8 photoreceptors. Proc. Natl. Acad. Sci. USA 96, 5055-5060.
3. Huang, M.-L., Hsu, C.-H., and Chien, C.-T., (2000) The proneural gene amos promotes multiple dendritic neuron formation in the Drosophila peripheral nervous system. Neuron 25, 57-67.
4. Pi, H., Wu, H.-R., and Chien, C.-T., (2001) A dual function of phyllopod in Drosophila external sensory organ development: cell fate specification of sensory organ precursor and its progeny. Development 128, 2699-2710.
5. Ou, C.-Y., Lin, Y.-F., Chen, Y.-J. and Chien, C.-T., (2002) Distinct protein degradation mechanisms mediated by Cul1 and Cul3 controlling Ci stability in Drosophila eye development. Genes & Develop. 16, 2403-2414.
6. Chou, Y.-H. and Chien, C.-T., (2002) Scabrous controls ommatidial rotation in the Drosophila compound eye. Develop. Cell 3, 839-850.
7. Ou, C.-Y., Pi, H. and Chien, C.-T., (2003) Control of protein degradation by E3 ubiquitin ligases in Drosophila eye development. Trends Genetics 19, 382-389.
8. Pi, H., Huang, S.-K., Tang, C.-Y., Sun, Y.-H. and Chien, C.-T., (2004) phyllopod is a target gene of proneural proteins in Drosophila external sensory organ development. Proc. Natl. Acad. Sci. USA 101, 8378-8383
9. Wu, J.-T., Lin S.-C., Hu, Y.-C. and Chien, C.-T., (2005) Neddylation and deneddylation regulate Cul1 and Cul3 protein accumulation. Nat. Cell Biol. 7, 1014-1020.
10. Ho, M. S., Tsai P.-I., and Chien, C.-T.* (2006) F-box proteins: the key to protein degradation. J. Biomedical Sci., 13: 181–191.
11. Wu, J.-T., Chan Y.-R. and Chien, C.-T.* (2006) Protection of cullin-RING E3 ligases by CSN-UBP12. Trends Cell Biol. 16(7):362-9.
12. Pi, H.-W., Chien, C.-T.* (2007) Getting the edge: neural precursor selection. J. Biomedical Sci. 14(4):467-73.
13. Ou CY, Wang CH, Jiang J, Chien CT*. (2007) Suppression of Hedgehog signaling by Cul3 ligases in proliferation control of retinal precursors. Dev Biol. 308(1):106-19.