Dr. Jun-Yi Leu 呂俊毅博士

分生所研究員

研究著作

  1. Siegal, M.L. and Leu, J.-Y. “On the nature and evolutionary impact of phenotypic robustness mechanisms.” Annu. Rev. Ecol. Evol. Syst. 45: 495-517 (2014).
  2. Gopinath, R.L., You, S.-T., Chien, K.-Y., Swamy, K.B., Yu, J.-S., Schuyler, S.C.* and Leu, J.-Y.*  “The Hsp90-dependent proteome is conserved and enriched for hub proteins with high levels of protein-protein connectivity.” Genome Biol. Evol. 6: 2851-2865 (2014).
  3. Kumaran, R., Yang, S.-Y. and Leu, J.-Y.* “Characterization of chromosome stability in diploid, polyploid and hybrid yeast cells.” PLoS One 8(7): e68094 (2013).
  4. Hsieh, Y.-Y., Hung, P.-H., Leu, J.-Y.* “Hsp90 regulates non-genetic variation in response to environmental stress.” Molecular Cell 50: 82-92 (2013).
  5. Chang, S.-L., Lai, H.-Y., Tung, S.-Y. and Leu, J.-Y.* “Dynamic large-scale chromosomal rearrangements fuel rapid evolution in yeast populations.” PLoS Genet. 9(1): e1003232 (2013).
  6. McDonald, M.J., Hsieh, Y.-Y., Yu, Y.-H., Chang, S.-L. and Leu, J.-Y. “The evolution of low mutation rates in experimental mutator populations of Saccharomyces cerevisiae.” Curr. Biol. 22: 1235-1240 (2012).
  7. Liu, I.-C., Chiu, S.-W., Lee, H.-Y. and Leu, J.-Y.* “The histone deacetylase Hos2 forms an Hsp42-dependent cytoplasmic granule in quiescent yeast cells.” Mol. Biol. Cell 23(7): 1231-1242 (2012).
  8. McDonald, M.J., Wang, W.C., Huang, H.-D.* and Leu, J.-Y.* “Clusters of nucleotide substitutions and insertion/deletion mutations are associated with repeat sequences.” PLoS Biol. 9(6): e1000622 (2011).
  9. Chang, S.-L. and Leu, J.-Y.* “A tradeoff drives the evolution of reduced metal resistance in natural populations of yeast.” PLoS Genet. 7(3): e1002034 (2011).
  10. Chou, J.-Y., Hung Y.-S., Lin, K.-H., Lee, H.-Y. and Leu, J.-Y.* “Multiple molecular mechanisms cause reproductive isolation between three yeast species.” PLoS Biol. 8(7): e1000432 (2010).
  11. Chou, J.-Y. and Leu, J.-Y.* “Speciation through cytonuclear incompatibility: insights from yeast, and implications for higher eukaryotes” BioEssays 32: 401-411 (2010).
  12. Ezov, T.K., Chang, S.-L., Frenkel, Z., Segre, A.V., Bahalul, M., Murray, A.W., Leu, J.-Y., Korol, A. and Kashi, Y. “Heterothallism in S. cerevisiae isolates from nature: effect of HO locus on the mode of reproduction.” Molecular Ecology 19: 121-131 (2010).
  13. Greig, D.* and Leu, J.-Y.* “Natural history of budding yeast.” Curr. Biol. 19: R886-890 (2009).
  14. Lee, H.-Y., Chou, J.-Y., Cheong, L., Chang, N.-H., Yang, S.-Y. and Leu, J.-Y.*“Incompatibility of nuclear and mitochondrial genomes causes hybrid sterility between two yeast species.” Cell 135: 1065-1073 (2008)
  15. Segre A. V., A. W. Murray andLeu, J.-Y.* “High-resolution mutation mapping reveals parallel experimental evolution in yeast.” PLoS Biol. 4: 1372-1385 (2006).
  16. Leu, J.-Y.* and Murray, A.W. “Experimental evolution of mating discrimination in budding yeast.” Curr. Biol. 16: 280-286 (2006)
  17. Leu, J.-Y. and Roeder, G.S. “The pachytene checkpoint in S. cerevisiae depends on Swe1-mediated phosphorylation of the cyclin-dependent kinase Cdc28.” Molecular Cell 4, 805-814 (1999)
  18. Leu, J.-Y. and Roeder, G.S. “The meiosisspecific HOP2 transcript utilizes a unique 5’ splice site.” Mol. Cell. Biol. 19, 7933-7943 (1999)
  19. Leu, J.-Y., Chua, P.R. and Roeder, G.S. “The meiosis-specific Hop2 protein of S. cerevisae ensures synapsis between homologous chromosomes.” Cell 94, 375-386 (1998)
* corresponding author
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