發現水解酶裁切修剪核糖核酸的原則

袁小琀老師的實驗室運用X光蛋白質結晶學，觀測出水解酶RNase T，如何篩選和分解特定序列及結構的核糖核酸。
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Contact

Prof. Dr. Yuan, Hanna

hanna@sinica.edu.tw

Original Publication

Hsiao, Y.-Y., Yang, C.-C, Lin C. L., Lin, J. L. J., Duh, Y. and Yuan*, H. S.
Structural basis for RNA trimming by RNase T in stable RNA 3′-end maturation

Nature Chemical Biology 7, 236-243 (2011) - DOI