果蠅視覺系統中膠細胞的分化調控與功能
我的研究主題在探討膠細胞在果蠅視覺系統發育中的分化調控 及功能。我們發展了在體外長期培養眼碟的方法，讓我們得以 觀察且研究膠細胞的分裂、遷移及分化。我們正在探討其中會 包裹感光細胞軸突的包裹膠細胞，探討其品系如何與其他膠細 胞品系分離，其分化如何在空間與時間上被調控，以及其如何 影響感光細胞的功能與軸突的投射。
- PDF, 1986-1988, Department of Biology, Yale University, USA
- Ph.D., 1986, Division of Biology, California Institute of Technology, USA
- BS, 1978, Department of Botany, National Taiwan University
- 1999, 中研院年輕學者研究成果獎
- 1999, 2004, 科技部傑出獎
- 1999-2004, 2004-2009, 科技部尖端計畫
- 2008, 教育部學術獎
- 2008, 侯金堆傑出榮譽獎
- Lee, Y.-M., Sun, Y. H. (2015) Maintenance of glia in the optic lamina is mediated by EGFR signaling by photoreceptors in adult Drosophila. PLoS Genetics 11(4): e1005187.
- Tsao, C. K., Ku, H. Y., Lee, Y. M., Huang, Y. F., Sun, Y. H. (2016) Long term ex vivo culture and live imaging of Drosophila larval imaginal discs. PLoS One 11(9): e0163744.
- Ku, H.-Y., Sun, Y. H. (2017) Notch-dependent epithelial fold determines boundary formation between developmental fields in the Drosophila antenna. PLoS Genetics 13(7): e1006898.
- Yeh, P.-A., Chu, W.-C., Liu, J.-Y., Sun, Y. H. (2018) Glial expression of disease-associated poly-glutamine proteins impairs the blood-brain barrier in Drosophila. Human Mol. Genet. 27: 2546–2562.
- Tsao, C.-K., Huang, Y. F., Sun, Y. H. (2020) Early lineage segregation of the retinal basal glia in the Drosophila eye disc. Scientific Reports 10: 18522.
