In our program, student learning takes place in research environment in which students benefit from interaction with researchers who are working at the frontiers of knowledge in their disciplines. Research is vigorous and pioneering and this creates a stimulating environment for study. Our staff are enthusiastic and committed to their subject. The enthusiasm and commitment generates an exciting and vibrant learning community.
The research in the Chromosome Biology focuses on the maintenance of chromosomes in cell division and the control of gene expression.
Projects cover virus entry and host cell signaling, virus replication and transcriptional control, protein engineering, T lymphocyte biology, and interleukin 15 activity, and bacterial physiology involving antibiotic target and resistance.
Focuses on the importance of gene function on cellular, organismic and developmental levels.
Projects cover interrogating neural development and degeneration by ES cells, neurodevelopmental disorders, Drosophila neural development and protein degradation control, mechanisms of motivation and memory, development of visual system, and prion biology.
Arabidopsis and rice are used as model systems to study plant physiology, plant gene regulation and its agricultural applications.
Focuses include mechanism of pre-mRNA splicing, RNA decay, regulation by noncoding RNA and RNA-associated diseases.
Macromolecular characteristics are being analyzed to unravel their structural-functional relationships by X-ray crystallographic, biophysical and biochemical approaches.
Research includes mechanisms of speciation and genetic buffering, interactions between nematodes and nematode-trapping fungi, cell growth and metabolic controls in the mammalian system, prokaryotes, protein turnover regulation and systems biology.
Biomedical sciences are a set of sciences applying portions of natural science or formal science, or both, to knowledge, interventions, or technology that are of use in healthcare or public health.
Chang, Wen
Molecular mechanism of vaccinia virus entry into mammalian hosts Cellular defense mechanisms and viral host range genes antagonizing host restriction
Chen, Hung-Ta
Mechanisms of Eukaryotic Transcription
Chen, Jun-An
Non-coding RNA Function during Motor Neuron Development, Degeneration, and Regeneration
Chen, Liuh-yow
Telomere Biology and Telomere Diseases
Chen, Sheng-hong
Lab for Cell Dynamics aims to quantify and model dynamics of signaling networks in single cells as the basis to control cellular behavior for therapeutic purposes
Cheng, Hwai-Jong
Axonal Connection, Hippocampus, and Aging
Cheng, Pei-Lin
Mechanisms of neuronal polarization and regeneration
Chien, Cheng-Ting
Dendrite arborization in development and diseases
Synapse formation and plasticity
Hsia, Kuo-Chiang
Molecular and structural basis of cell division
Hsiao, Chwan-Deng (David)
Structural and functional study of protein-DNA and protein-protein interaction by X-ray crystallography
Hsueh, Yi-Ping
Neuronal Morphogenesis
Neurodevelopmental disorders
Neurodegenration
Huang, Kuo Hua
Neural processing of social information in virtual reality
King, Chih-Yen
Molecular biology of amyloid and prions
Structural principle of amyloids
Kamino, Keita
Quantitative biology of adaptive cellular behavior
Leu, Jun-Yi
Yeast genomics and experimental evolution
Cell-cell communication and gene network regulation
Genetic and noise buffering
Li, Hsou-min
Protein sorting within cells
Developmental regulation of protein trafficking
Lin-Chao, Sue
Signal pathways govern the control of bacterial RNA degradation;
Function of RNA degradosome components
Function of growth-arrest genes during mouse brain development
RNA biology
Lin, Chien-Ling
Genome-Wide Analysis of the mRNA Splicing and Translation
Lin, Suewei
Molecular and neural mechanisms of motivation and memory
Lin, Wei-Hsiang
Quantitative microbiology; microfluidic experiments
Metabolism and cell growth; single-cell measurement and mathematical model
Ting, See-Yeun
Interbacterial interaction within microbial communities
Tsay, Yi-Fang
Molecular mechanism of Nitrate signaling and transport
Wang, Ting-Fang
Chromosome biology and fungal sexual development
Wang, Wei-Le
Immune regulation in the tissue barriers
Wei, Jen-Hsuan
Cytoskeleton and Organelle Biology
Mechanism of microtubule nucleation: r-TuRC assembly, targeting, and function in neuronal development
Wu, Yu-Wei
Neural circuit and glial network mechanisms underlying motor learning
Yuan, Hanna
Structural and functional studies of DNA and RNA metabolism
Chen, Guang-Chao
Functional analysis of PTPs in development and human diseases
Shih, Yu-Ling
Metabolic regulation of cell growth and division in E.coli
Mechanism of bacterial cell wall synthesis
Weng, Jui-Hsia
Drugging inter-organ communication against immune disorders
Yao, Chi-Kuang
Neuronal communication and neurodegenerative diseases
Wang, I-Hsuan (Jessica)
Cell biology of viral infections
Virus entry and egress
Wang, Shu-Ping
Molecular oncology, Cancer epigenetics
Biochemically defined cell free system
CRISPR-based genetic/epigenetic editing
Chiu, Shu-Ling
Synaptic Plasticity, Neural Development, Learning and Memory
Chou, Shen-Ju
Neural development, Developmental biology
Chou, Ya-Hui
Developmental Neurobiology, Neuronal circuitry, Insect Behavior
Hsu, Hwei-Jan
Developmental Biology, Stem cell Biology
Kao, Cheng-Fu
Chromatin structure and function
Metabolism on chromatin dynamics and epigenetics
Chromatin regulatory mechanisms in development and disease
Kuo, Hung-Chih
Stem Cell Biology
Molecular Embryology
Chiou, Jian-Geng
Developmental patterning in microbiology
Kuo, Chih-Horng
Utilize genomic, metagenomics, and bioinformatics tools to investigate microbial genome evolution and the diversity
Verslues, Paul E.
Drought related signaling and metabolism
Lin, Keng-hui
Physical Cell Biology lab aims to understand how physical factors such as dimensionality affect cellular behaviors and also how cells utilize physical principles to perform biological functions. Our lab adopt interdisciplinary approaches to solve these questions including quantitative microscopy, molecular perturbation, and microfabrication.
Chang, Tien-Hsien
Genome-wide bypass of essential genes
Genome architecture
Molecular mechanism of pre-mRNA splicing, mRNA export, and translation
In vivo roles of DExD/H-box proteins in RNA metabolism
Chen, Yun-Ru
Protein misfolding and neurodegenerative diseases
Hwang-Verslues, Wendy W.
Long term goals of the Hwang-Verslues laboratory are to decipher the links among circadian rhythm, core clock gene functions and stem cell (SC) fate/characteristics in tissue development and disease progression
Juan, Li-Jung
Epigenetic Regulation in Development and Disease
Lee, Chih-Hao
To understand bioenergetic controls of physiological processes that impact metabolic health
Lin, Kuo-I
The regulatory mechanisms in immune cell development and function
Lu, Joyce Jean
Efficiently reprogram somatic cell /stem cell fate by high throughput functional screens
Chang, Tsung Hsien
Innate immune responses in positive-strand RNA virus infection
Chen, Chien-Fu F.
Neurobiology of mammalian olfactory system
Hsieh, Po-Shiuan
The casual relationship between inflammation and obesity-associated metabolic syndrome and diabetes mellitus ; The therapeutic approach to prevent and treat metabolic syndrome and type II diabetes
Huang, Shih-Ming
Nuclear receptor coactivator functions
Huang, Eagle Yi-Kung
Oxytocin and related compounds in pain management
Modulation of LVV-hemorphins and angiotensin IV in the central nervous system
Development of new drugs for anesthesia and analgesia
Shieh, Yi-Shing
Cancer biology and tumor microenvironment
Signal transduction and epigeneticregulation
Molecular pathology
Head and Neck Oncology
Sung, Po-Yi
T Cell-Based Cancer Immunotherapy
Wang, Lan-Hsin
Molecular and genetic mechanism of the Hippo pathway in development and disease
Wu, Chin-Chen
Mechanisms and possible therapies of sepsis associated with septic shock, disseminated intravascular coagulation, or multiple organ failure
Wu, Gwo-Jang
Cellular and Molecular Mechanisms of Fertilization ; Gametogenesis and Embryo Implantation in Mammals
Yang, Sung-Sen
Human inherited channelopathy and blood pressure regulation
Genetic Engineering
Dr. Hsou-min Li / Program Coordinator (IMB)